2023 CCC Symposium

Building in vitro organelle interactions systems: bridging cell and synthetic biology

Wednesday, November 15, 2023

About the Organizers

Mary Mirvis is a postdoc in Wallace Marshall’s lab at UCSF, interested in understanding how organelles interact spatially, geometrically, and physically, and how these interactions cumulatively influence cell anatomy. She is studying mesoscale cell organization and organelle interactions in budding yeast using a combination of microscopy techniques and statistical modeling, as well as employing evidence synthesis methods to examine principles of organelle-level cell organization across eukaryotes.

Jie Shi (Postdoctoral Researcher) is a Biological Engineer, with expertise in computational biophysics and statistics. In the Cellular Engineering group, Jie works on  engineering immune cells using a combination of AI and structural biology and on designing de novo proteins.

Shankar Mukherji is an assistant professor of physics and cell biology at Washington University in St. Louis. The Mukherji group is interested in uncovering the quantitative principles by which the cell governs systems-level organelle biogenesis, at scales ranging from microscopic gene expression and signaling to mesoscopic properties of organelle number, size, and shape.

Will Prinz serves as the Chair of the Cell Biology Department at UT Southwestern. Dr. Prinz’s lab is dedicated to unraveling the intricate world of organelle biogenesis and intracellular lipid trafficking and homeostasis. Research topics include mechanisms and functions of lipid exchange at membrane contact sites, the formation and contributions of ER subdomains to lipid metabolism and organelle biogenesis, and the production of lipid droplets and lipoproteins, such as VLDL, within the ER. The Prinz Lab employs an array of scientific methodologies, including cell biology, biochemistry, genetics, and high-throughput screening.

Debra Singer serves as Managing Director for the Center for Cellular Construction, an NSF funded Science and Technology Center.